Tesa/IPA cartridge – 1 month supply

Tesamorelin and Ipamorelin are both peptide-based growth hormone secretagogues (GHS), but they function differently in the body. Here’s a detailed comparison of their similarities and differences:

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Similarities

1. Growth Hormone Stimulation
   • Both peptides stimulate the release of growth hormone (GH) from the pituitary gland.
2. Peptide-Based Structure
   • They are synthetic peptides that act on different receptors to induce GH secretion.
3. Therapeutic Uses
   • Used in contexts related to growth hormone deficiency, body composition improvement, and fat metabolism.
4. Minimal Impact on Prolactin & Cortisol
   • Unlike some other GH secretagogues (e.g., GHRP-2, GHRP-6), these peptides do not significantly elevate prolactin or cortisol levels.

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Differences

Feature	Tesamorelin	Ipamorelin
Mechanism of Action	Growth Hormone-Releasing Hormone (GHRH) Analog – Mimics GHRH to stimulate GH release	Growth Hormone Secretagogue Receptor (GHSR) Agonist – Mimics ghrelin to trigger GH release
Target Receptor	Acts on GHRH receptors in the pituitary gland	Binds to Ghrelin (GHSR-1a) receptors in the hypothalamus & pituitary
Primary Use	FDA-approved for HIV-associated lipodystrophy (reduces visceral fat)	Research peptide, studied for anti-aging, muscle growth, and GH stimulation
Fat Loss Effects	Strong fat-reducing effects, particularly in visceral fat areas	Mild fat loss, more focused on muscle growth and GH pulsation
Muscle Growth	Moderate effects on muscle mass	More effective for muscle growth and recovery
Administration	Subcutaneous injection (prescribed treatment)	Subcutaneous injection (research/clinical settings)
FDA Approval	Yes (Approved for lipodystrophy treatment)	No (Used in research & peptide therapy)
Duration of Action	Short-acting, requires daily administration	Short-acting but can be used multiple times per day
Side Effects	Possible increased IGF-1 levels, mild joint pain, fluid retention	Minimal side effects, no significant cortisol or prolactin spike

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Key Takeaways

• Tesamorelin is more targeted for fat loss, especially in visceral fat areas, and is FDA-approved for lipodystrophy treatment.
• Ipamorelin is primarily used for muscle growth, recovery, and anti-aging and is less likely to cause side effects.
• Different mechanisms: Tesamorelin mimics GHRH, while Ipamorelin mimics ghrelin but without the hunger-inducing effects.

 

Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.